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Genomics Institute of the Novartis Research Foundation

Scientific Associate, ADME
Location:  San Diego, California-San Diego 92121
Posted on: 10/29/2009 11:58:47 AM
Postion type: Full time
Job Code: JI10-029
Required Education: Bachelor's Degree
Salary:
 

DESCRIPTION
Job Code : JI10-029

We are seeking an individual with experience in high-throughput ADME assays and LC/MS/MS to profile drug candidates. The successful candidate will support drug discovery efforts as a member of the Metabolism and Pharmacokinetics group by conducting automated and manual assays. Assay responsibilities may include, but are not limited to, carrying out in vitro studies to assess metabolic clearance, plasma stability, plasma protein binding, DDI potential and Caco-2 permeability. The successful candidate also will be expected to operate, troubleshoot and perform routine repairs of LC/MS/MS instrumentation.

The Genomics Institute of the Novartis Research Foundation (GNF), located in the Torrey Pines area of San Diego, CA, is funded by the Novartis Research Foundation and dedicated to the development and application of new methods and techniques for genome-wide biological discovery and biomedical research. GNF provides a unique and challenging opportunity to combine exploratory biomedical research with pharmaceutical drug development in a highly interactive, multidisciplinary environment and state-of-the-art facilities. GNF offers excellent compensation and a great benefits package. Visit our website at www.gnf.org EOE

Please submit your CV and any supporting documents to:

Genomics Institute of the Novartis Research Foundation
Job Code: JI10-029
10675 John Jay Hopkins Drive
San Diego, CA 92121

Fax: 858/812-1670, or submit online to jobs@gnf.org
(subject line must include JI10-029)





REQUIREMENTS:
Required qualifications and experience:
•B.S./M.S. degree in chemistry, biology or a related discipline with at least two years of experience in HT-ADME or in HT-LC/MS(/MS) analysis.
•Expertise in small molecule LC/MS/MS analysis and in LC/MS/MS troubleshooting.
•Experience with using automated liquid handlers, such as Beckman FX or NX. Prior experience programming automated liquid handlers is a plus.
•Excellent laboratory skills for low-throughput ADME assays.
•High level of self-motivation and ability to thrive in a goal- and team-oriented setting.
• Excellent written and oral communication skills.