|
|
|
|
|
|
|
|
|
|
|
|
MedImmune, LLC
Associate Scientist II/Scientist I
Location: Gaithersburg,
Maryland
20878
Posted on:
10/16/2009 11:17:19 AM
Postion type:
Full time
Job Code:
02005
Required Education:
Master's Degree
Salary:
DESCRIPTION
My company shares my
passion for helping to improve
human health around the world.”
“This is My MedImmune.”
Those who join MedImmune feel a sense of ownership about their future. They thrive with a recognized leader in the biotechnology industry and the wholly-owned subsidiary of AstraZeneca plc.
Here, you will join passionate professionals who advance science, technology and medicine to develop products designed to help people live better lives. You will excel in an environment characterized by respect, integrity and growth opportunities…that encourages both individual contribution and collaborative entrepreneurial thinking. Our products and/or product candidates are designed to address areas of need in infection, oncology, respiratory disease and inflammation, cardiovascular/gastrointestinal disease and neuroscience. Explore a MedImmune career as we strive to better more lives, more often, around the world.
Title: Associate Scientist II/Scientist I
Location: MD, Gaithersburg - Corporate Headquarters
Req: 02005
Position Summary:
Major Duties and Responsibilities (including supervising others):
Design and perform experiments for developing robust and scalable primary recovery unit operations including cell lysis and inclusion body (IB) recovery. Candidate is expected to be the expert of primary recovery in Process Biochemistry, evaluating and applying new technologies in process development. Responsibilities may also include development and trouble shooting of chromatography and UF/DF unit operations for purification of novel molecules such as protein-drug conjugates, bi-specifics and proteins expressed in E.coli systems that require re-folding. Candidate is expected to design and execute studies to meet early stage process development objectives and timeline, as well as preparation of regulatory documents (INDs, CTAs, IMPDs).
Special Skills/Abilities:
• Theoretical knowledge and practical experience in primary recovery process development and scale up
• Expertise in homogenization/cell disruption, depth filtration, continuous centrifugation, tangential flow filtration, IB recovery, and precipitation/flocculation
• Knowledge and hands on experience with primary recovery equipment at lab scale and large scale
• Familiarity with process modeling techniques and statistical analysis
• Experience in developing protein refold or purification process for non-Mab molecules desired
• GMP experience. Familiarity with tech transfer to pilot and commercial manufacturing desired
• Experience writing regulatory documents
• Good oral and written communication skills
• Team work and collaborative
• Supervisory experience is a plus
REQUIREMENTS:
Job Complexity: Job is complex, requiring a thorough understanding of biochemical properties
of biopharmaceuticals, process development and scale up in support of product commercialization. Scientific and technical expertise in primary recovery is essential. Knowledge and experience in chromatography and filtration development is required.
Supervision: Reports directly to a Principal Scientist but is expected to work independently on a day-to-day basis.
May supervise B.S./M..S. scientists and engineers directly or in matrix
(Supervision required, level of independence)
Education: M.S., Ph.D. or equivalent in chemical engineering
Experience: Ph.D. with 1-3 years, M.S. with 5+ years or B.S. with 8+ years of relevant experience in
biotechnology and development of biopharmaceutical products
If you are interested in this position please —
Apply online at www.medimmune.com/careers and search for Req #. 02005
MedImmune is an Equal Opportunity Employer and does not discriminate on the basis of race, color, religion, gender, age, national origin, disability, veteran status, or any other characteristic protected by federal, state or local law.
|
|
 |
|
|
|
|
|
|
|
|
|