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Theravance, Inc. (formerly Advanced Medicine)

RAI/RAII
Location:  South San Francisco, California-San Francisco 94080
Posted on: 10/9/2009 4:51:49 PM
Postion type: Full time
Job Code: 09-025
Required Education: Bachelor's Degree
Salary:
 

DESCRIPTION
As a member of the Drug Metabolism and Pharmacokinetics (DMPK) team, the successful candidate will be responsible for supporting in vivo bioanalysis of blood and tissue samples from various pre-clinical species by LC-MS/MS. Additional responsibilities include in vitro DMPK efforts by performing metabolism and protein binding studies. The ability to manage work independently while working effectively in a team is required. The candidate will also be responsible for presentation of data at Department meetings, data analysis and maintaining accurate documentation of studies. The successful candidate will be highly motivated with excellent organizational and reporting skills and will help support drug discovery in the DMPK department.

Duties and Responsibilities
1. Perform bioanalysis from in vivo studies
2. Coordinate and execute in vitro DMPK studies
3. Analyze samples using mass spectrometry
4. Data analysis and upload
5. Maintain accurate records


REQUIREMENTS:
Applicants should possess a BS in Chemistry/Biology or related coursework and 2-5 years of relevant experience. Prior experience with in vivo bioanalysis and LC-MS/MS is a requirement. Prior experience with in vitro DMPK assays, metabolite identification, GLP and robotics is a plus. The candidate must be able to analyze data and note significant deviations and maintain detailed, accurate and comprehensible study documentation. Successful applicants will have excellent oral and written communication and organizational skills.