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Lab Support, A Division Of On Assignment
Director Immunology Pharmacodynamic
Location: South San Francisco,
California-San Francisco
94083
Posted on:
9/17/2009 4:20:25 PM
Postion type:
Full time
Job Code:
JS11D
Required Education:
NOT PROVIDED
Salary:
DESCRIPTION
The Department of Early Development Pharmacokinetics, Pharmacodynamics and Bioanalytical Sciences is a Translational Pharmacology group dedicated to helping to translate novel research discoveries into effective therapeutics for unmet medical needs. An important part of our success is the use of relevant and novel PD-biomarkers to help drive our decision making on which drugs to bring forward and how to dose them appropriately. We are currently looking for a highly skilled and passionate leader of our Immunology Pharmacodynamic Biomarkers group. The successful candidate will lead a large group of talented scientists and research associates to successfully integrate PD-Biomarkers strategies and assays into our preclinical and clinical development programs in the areas of Immunology, Infectious Diseases, Neurology, Tissue Growth and Repair. He/She will provide scientific leadership for the company's efforts to develop PD-biomarker strategies and novel assays to determine drug MOA, activity and relevant biological effects in patients. This candidate will be expected to form close collaborations with our Research Discovery, Diagnostics, Clinical ITGR, Safety and PKPD groups.
Primary responsibilities are as follows:
Provide scientific leadership for the company's Pharmacodynamic-Biomarker strategies for all non-oncology projects. Advance our understanding of the pharmacology of our drugs and disease. Integrate PD-markers into our drug development programs when and where appropriate. Provide first class strategic and scientific advice regarding PD-Biomarkers to Peer Review Committees and Senior Leadership. Drive scientific and technical innovation. Work with Departmental and Senior Leadership to prioritize Biomarker programs to ensure optimal use of resources.
REQUIREMENTS:
PhD or M.D./PH.D. in a relevant scientific field (e.g. Immunology, Pharmacology, Pathology, Molecular biology). A strong knowledge of PD biomarkers and their use in defining PK/PD and dose-response relationships is attractive, but not mandatory. A minimum of eight (8-10) years experience in basic, clinical or industrial research post PhD. A record of cutting edge research as evidenced by first- and/or senior-authored publications in top-tiered journals. Relevant industry experience is highly preferred, but not mandatory. Ability to build, lead and manage a large group of highly motivated scientists is required, as well as, influence and motivate others, both within direct supervisory and matrixed environments
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