DEDHAM, Mass., Dec. 8 /PRNewswire/ -- Signet Laboratories, Inc., a leading medical diagnostics/research company specializing in the development of monoclonal antibodies and diagnostic assays for cancer, infectious disease, and neurodegenerative disease, today announced the availability of Cyclin D1, MITF, and PCNA.
Cyclin D1 clone DCS-6 is a cell cycle marker that has been extensively studied in certain types of cancer including lymphoma, non-small cell lung cancer, and breast carcinoma.
Micropthalmia transcription factor (MITF) clone D5 regulates the development and survival of melanocytes and retinal pigment epithelium. MITF is expressed in the majority of primary and metastatic epithelioid malignant melanomas.
Proliferating Cell Nuclear Antigen (PCNA) is expressed in proliferating cells in a variety of tissues. PCNA expression in tumors is not fully understood, but PCNA appears to be a valuable marker for breast, prostate and colon cancer.
About Signet Laboratories, Inc.
Signet Laboratories, Inc. (Dedham, MA) is a leading medical diagnostics/research company specializing in the development of monoclonal antibodies and diagnostic assays for cancer, infectious disease, and neurodegenerative disease. Signet was created in 1989 as a commercial spinout of Johnson & Johnson's Cambridge Research Laboratories, Inc.
The Company was founded to continue the mission originally established at CRL -- the early detection and recurrence monitoring of patients with cancer and infectious disease. Signet has developed patented technology for diagnosis and recurrence monitoring and for risk assessment of asymptomatic patients in these areas. For more than a decade, the Company has aggressively maintained licensing and development programs, which are responsible for its broad patent and intellectual property estate.
Company Contact Immunohistochemistry
Colleen Scott Angela Thomas
Signet Laboratories, Inc. Signet Laboratories, Inc.
180 Rustcraft Road 180 Rustcraft Road
Dedham, MA 02026 Dedham, MA 02026
Phone: 781.915.1404 Phone: 781.915.1417
Fax: 781.461.2456 Fax: 781.461.2456
Signet Laboratories, Inc.
CONTACT: Colleen Scott, +1-781.915.1404, email@example.com, or AngelaThomas, +1-781.915.1417, firstname.lastname@example.org, both of SignetLaboratories, Inc.