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Compound Defeats Drug-Resistant Bacteria, Brown University Study


12/1/2011 7:03:30 AM

When drugs are developed to combat infection, bacteria fight back by coming up with a deterrent. A newly developed compound makes the bacteria vulnerable again. A particularly ingenious weapon in bacteria’s arsenal is the drug efflux pump—proteins located in the membranes of bacteria that can recognize and expel drugs that have breached the membranes. In some cases, the bacterial pumps have become so advanced they can recognize and expel drugs with completely different structures and mechanisms.

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