C. Difficile Yields to Novel Antibiotic, University of Calgary Study

2/3/2011 6:43:59 AM

MedPageToday -- The investigational antibiotic fidaxomicin was as effective as vancomycin for treating Clostridium difficile diarrhea, a phase III, noninferiority trial showed. And the new agent resulted in lower rates of recurrence within four weeks of the end of treatment (15.4% versus 25.3%, P=0.005), Thomas Louie, MD, of the University of Calgary in Alberta, and colleagues reported in the Feb. 3 issue of the New England Journal of Medicine.

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